We are interested in how the brain is able to perceive the external world. We focus on neural circuits in the early sensory pathway and aim to understand how these neural circuits perform specific computations. To investigate how neural circuits function we employ a combination of multi-photon imaging, electrophysiology, optogenetics and computational modelling

Exploring Neural Circuits

 Some examples of the methods we employ to interrogate neural circuits

Multi-photon imaging: An array of retinal bipolar cell terminals responding to a moving bar. Data acquired by in vivo multi-photon imaging of zebrafish retina expressing SyGCaMP6 in all retinal bipolar cells
Electrophysiology: Paired recording of mitral-mitral cell synapses in the main olfactory bulb
Optogenetics: An image stack through the glomerular layer of a mouse expressing YFP-tagged Channelrhodopsin-2
Computational modeling: A realistic model of a retinal ganglion cell and the excitatory and inhibitory synapses of the inner plexiform layer of the retina