We are interested in how the brain is able to perceive the external world. We focus on neural circuits in the early sensory pathway and aim to understand how these neural circuits perform specific computations. To investigate how neural circuits function we employ a combination of multi-photon imaging, electrophysiology, optogenetics and computational modelling

Exploring Neural Circuits

 Some examples of the methods we employ to interrogate neural circuits

Multi-photon imaging: Interneurons of the olfactory bulb responding to odours.  Data acquired by in vivo multi-photon imaging of GCaMP6 expressed by all inhibitory neurons.
Electrophysiology: Paired recording of mitral-mitral cell synapses in the main olfactory bulb
Optogenetics: An image stack through the glomerular layer of a mouse expressing YFP-tagged Channelrhodopsin-2
Computational modeling: A realistic model of a retinal ganglion cell and the excitatory and inhibitory synapses of the inner plexiform layer of the retina