Johnston Lab

2025

New, L.E., Wang, N., Smith, H.E., Birks, R., Afridi, S.K., Griffiths, J.C., Hains, R., Johnston, J. & Filippi, B.M. (2025) Insulin evokes release of endozepines from astrocytes of the NTS to modulate glucose metabolism in male rats. Mol Metab, 102255.

Pantiru A. D., Van de Sompele S., Ligneul C., Chatelain C. Barrea C., Lerch J. P., Filippi, B. M., Alkan S., De Baere E. Johnston J. Clapcote S. C. (2025) Autistic behavior is a common outcome of biallelic disruption of PDZD8 in humans and mice. Molecular Autism

2024

Conway M., Oncul M., Allen K., Zhang Z., Johnston J. (2024) Perceptual constancy for an odor is acquired through changes in primary sensory neurons. Sci Adv 10, eado9205 .

New L. E., Wang N., Khan S., Griffiths J. C., Hains R., Johnston J., Filippi B. M. (2024) Insulin evokes release of endozepines from astrocytes of the NTS to modulate glucose metabolism, BioRxiv 10.1101/2024.05.03.592384

Armstrong P., Güngör H., Anongjanya P., Tweedy C, Parkin E., Johnston J., Carr I. M., Dawson N., and Steven J. Clapcote (2024) Protective effect of PDE4B subtype-specific inhibition in an App knock-in mouse model for Alzheimer’s disease.  Neuropsychopharmacology. 10.1038/s41386-024-01852-z

2023

Conway M., Oncul M., Allen K., and  Johnston J. (2023) Perceptual constancy for an odour is acquired through changes in primary sensory neurons, BioRxiv: https://doi.org/10.1101/2023.11.17.567529 

2022

Johnson, E., Clark, M., Oncul, M., Pantiru, A., MacLean, C., Deuchars, J., Deuchars, S.A. & Johnston, J. (2022) Graded spikes differentially signal neurotransmitter input in cerebrospinal fluid contacting neurons of the mouse spinal cord. iScience, 105914. 10.1016/j.isci.2022.105914

Moya-Díaz J., James B., Esposti F., Johnston J., and Lagnado L. (2022). Diurnal changes in the efficiency of information transmission at a sensory synapse. Nat Communications. 13, 2613.

2021

Johnston J. (2021) Pharmacology of A-Type K⁺ Channels. In: . Handbook of Experimental Pharmacology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/164_2021_456

Jose Moya-Diaz, Ben James, Federico Esposti, Jamie Johnston, Leon Lagnado (2021) Diurnal modulation of multivesicular release controls the efficiency of information transmission at a sensory synapse. BioRxiv: https://doi.org/10.1101/2021.09.12.459944

2020

Emily Johnson, Marilyn Clark, Claudia MacLean, James Deuchars, Susan A Deuchars, Jamie Johnston (2020) Graded calcium spikes differentially signal neurotransmitter input in cerebrospinal fluid contacting neurons of mouse spinal cord BioRxiv: https://doi.org/10.1101/2020.09.18.303347

2019

Jamie Johnston, Sofie-Helene Seibel, Léa Simone Adele Darnet, Sabine Renninger, Michael Orger, & Leon Lagnado (2018) A retinal circuit generating a dynamic predictive code for oriented features.Neuron 102 doi: https://doi.org/10.1016/j.neuron.2019.04.002

2015

Johnston, J., and Lagnado, L. (2015). General features of the retinal connectome determine the computation of motion anticipation. Elife 4, 10.7554/eLife.06250.

Picao-Osorio, J., Johnston, J., Landgraf, M., Berni, J., and Alonso, C.R. (2015). MicroRNA-encoded behavior in Drosophila. Science Nov 350(6262):815-20

2014

Johnston, J., Ding, H., Seibel, S.H., Esposti, F., and Lagnado, L. (2014). Rapid mapping of visual receptive fields by filtered back projection: application to multi-neuronal electrophysiology and imaging. J Physiol 592, 4839-4854. Code available here

Fekete, A., Johnston, J., and Delaney, K.R. (2014). Presynaptic T-type Ca2+ channels modulate dendrodendritic mitral-mitral and mitral-periglomerular connections in mouse olfactory bulb. J Neurosci 34, 14032-14045.

2013

Esposti, F., Johnston, J., Rosa, J., Leung, K.-M., and Lagnado, L. (2013). Olfactory Stimulation Selectively Modulates the OFF Pathway in the Retina of Zebrafish. Neuron 79, 97-110    

2012

Johnston, J., and Lagnado, L. (2012). What the Fish’s Eye Tells the Fish’s Brain. Neuron 76, 257-259.

Johnston, J., Esposti, F., and Lagnado, L. (2012). Color vision: retinal blues. Curr Biol 22, R637-R639.

2010

Johnston, J., Forsythe, I.D., and Kopp-Scheinpflug, C. (2010). Going native: voltage-gated potassium channels controlling neuronal excitability. J Physiol 588, 3187-3200.

Johnston, J., and Delaney, K. (2010). Synaptic activation of T-type Ca2+ channels via mGluR activation in the primary dendrite of mitral cells. J Neurophysiol 103, 2557-2569.

2009

Johnston, J., Postlethwaite, M., and Forsythe, I.D. (2009). The impact of synaptic conductance on action potential waveform: evoking realistic action potentials with a simulated synaptic conductance. J Neurosci Methods 183, 158-164.          

2008

Johnston, J., Griffin, S.J., Baker, C., Skrzypiec, A., Chernova, T., and Forsythe, I.D. (2008). Initial segment Kv2.2 channels mediate a slow delayed rectifier and maintain high frequency action potential firing in medial nucleus of the trapezoid body neurons. J Physiol 586, 3493-3509.

Johnston, J., Griffin, S.J., Baker, C., and Forsythe, I.D. (2008). Kv4 (A-type) potassium currents in the mouse medial nucleus of the trapezoid body. Eur J Neurosci 27, 1391-1399.

2006

Wong, A.Y., Billups, B., Johnston, J., Evans, R.J., and Forsythe, I.D. (2006). Endogenous activation of adenosine A1 receptors, but not P2X receptors, during high-frequency synaptic transmission at the calyx of Held. J Neurophysiol 95, 3336-3342.